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Higher Risk of Cardiovascular Disease Associated with Smaller SizeFractioned Particulate Matter

发布时间:2021/08/31

Peng Yin(殷鹏),Jianping Guo,Lijun Wang(王黎君),Wenhong Fan,Feng Lu,Moning Guo,Silvia Moreno,Ying Wang,Hao Wang,Maigeng Zhou(周脉耕),Zhaomin Dong

ABSTRACT: No nationwide studies have examined the associations between mortality risk and PM1 (PM with an aerodynamicdiameter of <1 μm) due to the scarcity of monitoring data of PM1. On the basis of newly released national scale PM1 data, weperformed a time series analysis to elucidate the cause-specific mortality risk caused by PM1 exposure in China. During the period

from January 2014 to December 2017, the PM1 levels in 65 cities of China were on average 37 ± 32 μg/m3. Pooled results indicateda 10 μg/m3 increase in the PM1 level was associated with a 0.19% [95% confidence interval (CI) of 0.090.28%] increased risk innonaccidental mortality, which was almost the same as that for PM2.5 (0.18%, 95% CI of 0.080.27%) and PM10 (0.17%, 95% CI of0.010.24%). By comparison, the magnitude increased to 0.29% (0.120.47%) in cardiovascular disease for each 10 μg/m3 uptick inPM1, which was significantly higher than that related to PM2.5 and PM10 exposure. This nationwide study supported the notion thatPM1 may be a higher risk factor for cardiovascular disease, which suggests rapid action is warranted to put more effort into mitigatingthe emissions of finer particulate matters. 

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